Multimedia in Biochemistry and Molecular Biology Education Proteopedia: 3D Visualization and Annotation of Transcription Factor–DNA Readout Modes
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چکیده
From the ‡Molecular and Computational Biology Program, Departments of Biological Sciences, Chemistry, and Physics and Astronomy, University of Southern California, 1050 Childs Way, Los Angeles, California 90089 §La Cañada High School, 4463 Oak Grove Drive, La Cañada Flintridge, California 91011 ¶Flintridge Preparatory School, 4543 Crown Avenue, La Cañada Flintridge, California 91011 ‡‡Harvard/MIT MD-PhD Program, Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts 02115 §§Department of Microbiology, University of Massachusetts, 639 North Pleasant Street, Amherst, Massachusetts 01003
منابع مشابه
Proteopedia: 3D visualization and annotation of transcription factor-DNA readout modes.
3D visualization assists in identifying diverse mechanisms of protein-DNA recognition that can be observed for transcription factors and other DNA binding proteins. We used Proteopedia to illustrate transcription factor-DNA readout modes with a focus on DNA shape, which can be a function of either nucleotide sequence (Hox proteins) or base pairing geometry (p53). © 2012 by The International Uni...
متن کاملProteopedia: A collaborative, virtual 3D web-resource for protein and biomolecule structure and function.
from the publication describing the structure, automatically generated ‘‘scene links’’ for ligands in the structure, and coloring by evolutionary conservation [5] (e.g. luciferase, 2d1s [6]). Instructors have also created pages as tutorials to either project in class or assign for students to read (e.g. tutorials on structural templates [7], serine proteases [8], and Ramachandran plots [9]). On...
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Proteopedia is a collaborative, 3D web-encyclopedia of protein, nucleic acid and other biomolecule structures. Created as a means for communicating biomolecule structures to a diverse scientific audience, Proteopedia (http://www.proteopedia.org) presents structural annotation in an intuitive, interactive format and allows members of the scientific community to easily contribute their own annota...
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Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...
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تاریخ انتشار 2012